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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Exp Neurol. 2020 Mar 3;328:113272. doi: 10.1016/j.expneurol.2020.113272

Figure 13. CCR5 expression in HIV DSN Patient sural nerve: IHC.

Figure 13.

Merged digital indirect fluorescent photomicrographs of axial and longitudinal sections from a HIV+ patient with DSN show clusters of endoneurial CCR5+ CD68+ monocytes/macrophages at low (A) and higher magnification (B and C, white arrows), and an endoneurial microvessel (white outline) with multiple luminal adherent CCR5+ CD68+ monocytes (white arrow heads, D). Less common endoneurial clusters of CCR5+ CD4+ T-lymphocytes (E) and CCR5+ CD8+ T-lymphocytes (F) are also observed in this specimen.