Figure 22.

Comparison of deconvoluted (A) ETD and (B) 193 nm UVPD mass spectra of the N-terminal tail of H3K4me1K9me2K14acK18-acK23acK27acK36me3 (50 residues, 8+ charge state) showing fragment ion maps, P-score, sequence coverage, and labeled PTM site-localizing ions. Residues are shaded to indicate modifications: red indicates acetylation, blue indicates dimethylation, green indicates methylation, and purple indicates trimethylation. Reproduced with permission from ref 164. Copyright 2018 American Chemical Society.