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. 2020 Apr 9;10:6118. doi: 10.1038/s41598-020-63340-w

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Obesity-induced alterations of the microbiota in a substrain-dependent manner. Microbial communities in LFD- and HFD-fed mice of each B6 substrain were analyzed. (A) NMDS diagram of microbial communities in the B6 substrains. Each dot represents the microbiome composition of a single animal. Light colors: LFD. Dark colors: HFD. Blue: B6J. Green: B6JHanZtm. Yellow: B6NCrl. (B) Frequencies of the most common phyla in the intestinal content from LFD- and HFD-fed mice of each B6 substrain.