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. 2020 Apr 3;11:558. doi: 10.3389/fimmu.2020.00558

Figure 7.

Figure 7

Adalimumab decreased intrauterine inflammation in amniotic fluid. (A) Cytokine and prostaglandins concentrations were measured in amniotic fluid by multiplex ELISA. IL-1β, IL-6, IL-8/CXCL8, TNFα, CCL2/MCP1, CCL4/MIP1β, IL-1ra, IL-10, but not GM-CSF, PGF2α and PGE2 were significantly decreased upon Adalimumab treatment. (B) Adalimumab decreased frequency of neutrophils in amniotic fluid. Data are mean ± SEM, *p < 0.05 vs. controls (Ctrl n = 17–25; LPS n = 16–19; Adalimumab n = 11; Mann–Whitney U-test).