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. 2020 Apr 3;8:196. doi: 10.3389/fcell.2020.00196

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Copyright © 2020 Hu, Yang, Lu, Deng, Li, Zhu, Zhang, Hu, Hu, Xia, He, Han, Liu, Kang, Li and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Venn diagrams showing the number of nearby DEGs of differential peaks between different stages of early ovarian development. (A,C,E) Overlap of significantly upregulated genes identified by RNA-seq with nearby genes of significantly increased ATAC-seq peaks between P0 vs. E15, P4 vs. P0, and P28 vs. P4, respectively. (B,D,F) Overlap of significantly downregulated genes identified by RNA-seq with nearby genes of significantly decreased ATAC-seq peaks between P0 vs. E15, P4 vs. P0, and P28 vs. P4, respectively.