Table 2:

The standards grading of GRADE in outcome indicator

Quality assessment
Outcome indicator	Included study	Design	Quality of methodology	Circumstantial evidence	Heterogeneity	Precision	Publication bias	Hierarchy of evidence quality
Ldl-c	10								Rcts	Middle rank1	No	High rank	High rank	Middle rank2	Middle rank
Hdl-c	8	Rcts	Middle rank1	No	High rank	High rank	Middle rank2	Middle rank
Tc	7	Rcts	Middle rank1	No	High rank	High rank	Middle rank2	Middle rank
Tg	8	Rcts	Middle rank1	No	High rank	High rank	Middle rank2	Middle rank
Non-hdl-c	7	Rcts	Middle rank1	No	High rank	High rank	Middle rank2	Middle rank
Hs-crp	7	Rcts	Middle rank1	No	High rank	High rank	Middle rank2	Middle rank

¹Selective reporting (reporting bias);

²Publication bias; RCTs: Randomized Controlled Trials