Table 2.

Subgroup analysis for asthma/wheeze base on categorical BMI (adjusted).

Group	Numbers (Asthma/Wheeze)	Asthma		Wheeze
		OR (95% CI); P	I2	OR (95% CI); P	I2
Maternal obesity
By sample size
Total sample size <6000	3/7	1.60 (1.20–2.13); 0.001	48.6%	1.68 (1.25–2.26); 0.001	73.0%
Total sample size ≥6000	3/6	1.50 (1.34–1.66); <0.001	0.0%	1.28 (1.10–149); 0.001	44.9%
By region
America	3/2	1.39 (1.20–1.60); <0.001	0.0%	3.12 (1.74–5.13); <0.001	0.0%
Asia	NA/1	NA	NA	1.67 (0.73–3.81); 0.223	NA
Europe	3/10	1.63 (1.38–1.94); <0.001	19.4%	1.29 (1.14–1.45); <0.001	56.2%
By weight modality
Medical records	2/4	1.40 (1.12–1.74); 0.003	0.0%	1.24 (1.00–1.55); 0.052	32.7%
Self-report	4/9	1.54 (1.34–1.77); <0.001	32.3%	1.48 (1.22–1.79); <0.001	70.4%
By diagnosis of asthma
Doctor diagnosis	5/5	1.50 (1.33–1.69); <0.001	23.9%	1.48 (1.19–1.86); 0.001	36.1%
Parental report	1/8	1.53 (1.04–2.26); 0.032	NA	1.29 (1.11–1.51); 0.001	63.0%
Maternal overweight
By sample size
Total sample size <6000	4/8	1.19 (0.95–1.49); 0.123	47.1%	1.19 (0.95–1.49); 0.032	0.0%
Total sample size ≥6000	3/5	1.21 (1.13–1.30); <0.001	0.0%	1.21 (1.13–1.30); 0.022	41.9%
By region
America	2/1	1.20 (1.06–1.38); 0.005	0.0%	1.58 (0.75–3.31); 0.226	NA
Asia	NA/1	NA	NA	1.11 (0.72–1.71); 0.635	NA
Europe	5/11	1.21 (1.06–1.37); 0.004	30.9%	1.07 (1.02–1.11); 0.003	0.0%
By weight modality
Medical records	1/3	1.14 (0.90–1.45); 0.282	NA	1.12 (1.03–1.23); 0.013	0.0%
Self-report	6/10	1.21 (1.12–1.31); <0.001	10.6%	1.06 (1.01–1.12); 0.028	2.7%
By diagnosis of asthma
Doctor diagnosis	4/4	1.22 (1.14–1.31); <0.001	0.0%	1.16 (1.03–1.30); 0.013	0.0%
Parental report	3/9	1.14 (0.86–1.51); 0.362	57.9%	1.06 (1.01–1.10); 0.019	0.0%

BMI, body mass index; OR, odds ratio; 95% CI, 95% confidence interval; I², inconsistency index; NA, not available.