Table 2.
Hepatocellular carcinoma-related targets of Huachansu capsules (HCSCs).
| Number | Protein name | Gene name |
|---|---|---|
| 01 | Steroid 5 Alpha-Reductase 1 | SRD5A1 |
| 02 | Aldo-Keto Reductase Family 1 Member B10 | AKR1B10 |
| 03 | Nuclear Receptor Subfamily 3 Group C Member 1 | NR3C1 |
| 04 | Solute Carrier Family 10 Member 1 | SLC10A1 |
| 05 | Vitamin D Receptor | VDR |
| 06 | Tyrosine Aminotransferase | TAT |
| 07 | Hydroxysteroid 11-Beta Dehydrogenase 2 | HSD11B2 |
| 08 | Androgen Receptor | AR |
| 09 | ATPase Na+/K+ Transporting Subunit Alpha 1 | ATP1A1 |
| 10 | Solute Carrier Family 10 Member 2 | SLC10A2 |
| 11 | UDP Glucuronosyltransferase Family 2 Member B7 | UGT2B7 |
| 12 | Cytochrome P450 Family 27 Subfamily B Member 1 | CYP27B1 |
| 13 | Cytochrome P450 Family 3 Subfamily A Member 4 | CYP3A4 |
| 14 | Microtubule-associated protein tau | MAPT |
| 15 | Opioid Receptor Mu 1 | OPRM1 |
| 16 | Opioid Receptor Delta 1 | OPRD1 |
| 17 | Opioid Receptor Kappa 1 | OPRK1 |
| 18 | Muscleblind Like Splicing Regulator 2 | MBNL2 |
| 19 | Muscleblind Like Splicing Regulator 3 | MBNL3 |
| 20 | Butyrylcholinesterase | BCHE |
| 21 | Acetylcholinesterase (Cartwright Blood Group) | ACHE |
| 22 | ATP Binding Cassette Subfamily B Member 11 | ABCB11 |
| 23 | Serpin Family A Member 6 | SERPINA6 |
| 24 | Glucose-6-Phosphate Dehydrogenase | G6PD |
| 25 | Gamma-Aminobutyric Acid Type B Receptor Subunit 1 | GABBR1 |
| 26 | G Protein-Coupled Bile Acid Receptor 1 | GPBAR1 |
| 27 | Nuclear Receptor Subfamily 1 Group H Member 4 | NR1H4 |
| 28 | Nuclear Receptor Subfamily 1 Group I Member 3 | NR1I3 |
| 29 | Sex Hormone Binding Globulin | SHBG |
| 30 | Bradykinin Receptor B2 | BDKRB2 |
| 31 | ATP Binding Cassette Subfamily C Member 4 | ABCC4 |
| 32 | ST6 Beta-Galactoside Alpha-2,6-Sialyltransferase 1 | ST6GAL1 |
| 33 | Matrix Metallopeptidase 3 | MMP3 |
| 34 | Matrix Metallopeptidase 1 | MMP1 |
| 35 | Matrix Metallopeptidase 10 | MMP10 |
| 36 | Matrix Metallopeptidase 8 | MMP8 |
| 37 | Matrix Metallopeptidase 12 | MMP12 |
| 38 | Matrix Metallopeptidase 13 | MMP13 |
| 39 | Growth Factor, Augmenter Of Liver Regeneration | GFER |
| 40 | Angiotensin I Converting Enzyme | ACE |
| 41 | Angiotensin I Converting Enzyme 2 | ACE2 |
| 42 | ADAM Metallopeptidase Domain 17 | ADAM17 |
| 43 | Carboxyl Ester Lipase | CEL |
| 44 | Cytochrome P450 Family 17 Subfamily A Member 1 | CYP17A1 |
| 45 | Matrix Metallopeptidase 2 | MMP2 |
| 46 | Eukaryotic Translation Initiation Factor 2 Alpha Kinase 3 | EIF2AK3 |
| 47 | Caspase 3 | CASP3 |
| 48 | MYB Proto-Oncogene, Transcription Factor | MYB |
| 49 | Poly(ADP-Ribose) Polymerase 1 | PARP1 |
| 50 | Interferon Regulatory Factor 3 | IRF3 |
| 51 | Cytochrome P450 Family 3 Subfamily A Member 5 | CYP3A5 |
| 52 | TNF Receptor Superfamily Member 10a | TNFRSF10A |
| 53 | Glycogen Synthase Kinase 3 Beta | GSK3B |
| 54 | Cannabinoid Receptor 1 | CNR1 |
| 55 | Estrogen Receptor 1 | ESR1 |
| 56 | Estrogen Receptor 2 | ESR2 |
| 57 | Cannabinoid Receptor 2 | CNR2 |
| 58 | Carbonic Anhydrase 1 | CA1 |
| 59 | Carbonic Anhydrase 2 | CA2 |
| 60 | Nuclear Receptor Subfamily 3 Group C Member 2 | NR3C2 |
| 61 | Sonic Hedgehog | SHH |
| 62 | Histone Deacetylase 1 | HDAC1 |
| 63 | Histone Deacetylase 3 | HDAC3 |
| 64 | Histone Deacetylase 2 | HDAC2 |
| 65 | Fatty Acid Binding Protein 1 | FABP1 |
| 66 | Progesterone Receptor | PGR |
| 67 | Solute Carrier Family 22 Member 2 | SLC22A2 |
| 68 | Steroid 5 Alpha-Reductase 2 | SRD5A2 |
| 69 | Hydroxysteroid 17-Beta Dehydrogenase 12 | HSD17B12 |
| 70 | 5-Hydroxytryptamine Receptor 2B | HTR2B |
| 71 | Epidermal Growth Factor Receptor | EGFR |
| 72 | Erb-B2 Receptor Tyrosine Kinase 2 | ERBB2 |
| 73 | Erb-B2 Receptor Tyrosine Kinase 4 | ERBB4 |
| 74 | Erb-B2 Receptor Tyrosine Kinase 3 | ERBB3 |
| 75 | Kruppel Like Factor 5 | KLF5 |
| 76 | Carbonic Anhydrase 3 | CA3 |
| 77 | Secreted Frizzled Related Protein 1 | SFRP1 |
| 78 | Coagulation Factor II Thrombin Receptor | F2R |
| 79 | Monoglyceride Lipase | MGLL |
| 80 | Galactosidase Beta 1 | GLB1 |
| 81 | Histone Deacetylase 6 | HDAC6 |
| 82 | Solute Carrier Family 5 Member 1 | SLC5A1 |