Table 2.
ncRNAs involved in Th1 cells.
| ncRNA | Target gene | Biological function | Reference |
|---|---|---|---|
| miR-21 | N/A | Inhibits the differentiation of Th1 cells by regulating IL-12 secretion |
(36) |
| miR-29 | T-bet and Eomes | Promotes the differentiation of Th1 cells | (35) |
| miR-148 | Bim | Contributes to Th1 cell development | (37, 38) |
| miR-142a-5p | SOCS1 and TGFBR1 |
Promotes the differentiation of Th1 cells | (39) |
| miR-31 | T-bet and FOXO1 | Negatively regulates T cell activation and migratory activity of Th1 cells | (40) |
| miR-150 | SLC2A1 | Promotes IL-10+ Th1 cell differentiation | (42) |
| LncRNA-Ifng-AS1 (NeST, Tmevpg1) |
Ifng | Promotes the differentiation of Th1 cells | (43) |