Table 4.
ncRNAs involved in Th17 cells.
| ncRNA | Target gene | Biological function | Reference |
|---|---|---|---|
| miR-155 | SOCS1 | Enhances the differentiation of Th17 cells and the production of IL-17 | (53) |
| miR-223 | Roquin-1 | Regulates mDCs-induced Th17 cell differentiation | (55) |
| miR-21 | Smad7 | Promotes the differentiation of Th17 cells through smad/TGF-β signaling pathway | (56) |
| miR-183C | Foxo1 | Promotes the differentiation of Th17 cells | (57) |
| miR-210 | HIF-1α | Inhibits Th17 cell differentiation | (59) |
| LincRNA-p21 | HIF-1α | Stabilizes HIF-1α expression and function | (60) |
| LncRNA- 1700040D17Rik |
RORγt | Inhibits the differentiation of Th17 cells | (61) |