Table 5.

ncRNAs involved in Tfh cells.

ncRNA	Target gene	Biological function	Reference
miR-17~92	Rora and PHLPP2	Promotes the differentiation and migration of Tfh cells	(69, 71)
miR-92a	KLF2 and PTEN	Promotes Tfh cell development	(72)
miR-31	CD40L and SAP	Inhibits the ability of Tfh cells to support B cells	(73)
miR-155	Peli1	Promotes the differentiation of Tfh cells and the expression of CD40L	(75)
miR-146a and miR-146b	ICOS and CD40	Regulate ICOS–ICOSL and CD40-CD40L signaling to limit the accumulation of Tfh cells and GC responses	(77, 78)
Lnc-Malat1	N/A	Increases in T cells and plays a positive role in secreting proinflammatory cytokine IL-21	(79)