Table 2.
Days | Diagnostics | Treatment | Aim |
---|---|---|---|
Ceasarean section | Basic blood count, C-reactive protein, blood chemical values, hemolysis markers, coagulation factors and descriptive, antiphospholipid antibodies, Coombs test, plasma ADAMTS13 activity, and antinuclear antibodies |
Transfer to ICU | To exclude TTP, antiphospholipid syndrome, SLE, and autoimmune hemolytic anemia |
Postpartum day 1 | Plasma C3 and C4 levels, Complement terminal complex-level, C4A and C4B genetic testing | Plasma exchange | |
Postpartum day 2 | Hepatitis B and C, HIV, and aHUS genetic tests (Complement system) |
Plasma exchange, Hemodialysis |
To exclude viral hepatitis as a cause of liver damage |
Postpartum day 3 | Stool sample testing the pathogens causing typical HUS | Transfer back to Women's Hospital recovery room were observation and symptomatic therapy continued | To exclude typical HUS |
Postpartum day 4 | Basic laboratory tests concerning hemolysis, liver and kidney function, platelets, and coagulation | Hemodialysis, Transfer to the department of Nephrology, first dose of Eculizumab |
Diagnosis of aHUS was placed |
Postpartum day 5 | Basic laboratory tests concerning hemolysis, liver and kidney function, platelets, and coagulation | ||
Postpartum day 6 | Basic laboratory tests concerning hemolysis, liver and kidney function, platelets, and coagulation | Hemodialysis |