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. 2019 Jun 7;70(8):1580–1588. doi: 10.1093/cid/ciz481

Table 2.

Summary of Invasive Pneumococcal Disease Episodes per 1000 Blood Cultures in Hospitalized Children Aged <5 Years, by Time Period

Blood cultures (n) IPD (n) IPD detection rate (95% CI) VT (n) VT detection rate (95% CI) NVT (n) NVT detection rate (95% CI)
Pre-PCV (2012–2014) 11 170 42 3.76 (2.71–5.08) 39 3.49 (2.48–4.77) 3 0.27 (.05–.78)
Post-PCV (2016–2018) 9425 22 2.33 (1.46–3.53) 19 2.01 (1.21–3.15) 3 0.32 (.07–.09)
Early post-PCV (2016–2017) 6556 16 2.44 (1.40–3.96) 15 2.29 (1.28–3.77) 1 0.15 (.04–.85)
Late post-PCV (2018) 2869 6 2.09 (.77–4.55) 4 1.39 (.38–3.57) 2 0.70 (.08–2.51)

Abbreviations: CI, confidence interval; IPD, invasive pneumococcal disease; NVT, nonvaccine type; PCV, pneumococcal conjugate vaccine; VT, vaccine type.