Table 5.

Most Common Causes of All-cause Mortality by Preferred Terms (Full Analysis Set)

	Through Week 24 Post-HCT, n (%)		Through Week 48 Post-HCT, n (%)
	Letermovir	Placebo	Letermovir	Placebo
Total patients in population	325	170	325	170
Patients who died	32 (9.8)	27 (15.9)	61 (18.8)	40 (23.5)
AMLa	7 (2.2)	7 (4.1)	12 (3.7)	10 (5.9)
GVHDb	2 (0.6)	3 (1.8)	7 (2.2)	7 (4.1)
Sepsisc	4 (1.2)	3 (1.8)	6 (1.8)	4 (2.4)
Pneumonia	1 (0.3)	1 (0.6)	2 (0.6)	3 (1.8)
Respiratory failured	2 (0.6)	0 (0.0)	7 (2.2)	1 (0.6)
ALLe	2 (0.6)	1 (0.6)	3 (0.9)	1 (0.6)
Multiple organ dysfunction syndrome	2 (0.6)	2 (1.2)	2 (0.6)	2 (1.2)
Septic shock	1 (0.3)	2 (1.2)	2 (0.6)	2 (1.2)

Note that this table only lists the most common causes of all-cause mortality. Every patient is counted a single time for each applicable row and column.

Abbreviations: ALL, acute lymphatic leukemia; AML, acute myeloid leukemia; GVHD, graft-versus-host disease; HCT, hematopoietic cell transplantation.

^aIncludes AML and recurrent AML.

^bIncludes GVHD, acute GVHD, and gastrointestinal GVHD.

^cIncludes Enterococcal sepsis, Klebsiella sepsis, and Neutropenic sepsis.

^dIncludes acute respiratory failure.

^eIncludes ALL and recurrent ALL.