Figure 5.

Genomic changes and biological functions of prognostic tumor microenvironment-related genes. (A) The genetic alteration of the top 10 tumor microenvironment-related altered genes using the cBioPortal database. (B) The network included 99 nodes, including 49 query genes and the 50 most frequently altered neighbor genes (23 out of 49 were related to the 50 genes). The associations between tumor microenvironment-related genes and anticancer drugs are shown. (C) Gene ontology analysis of the prognostic tumor microenvironment-related genes. (D) Top 10 enriched KEGG pathways for the prognostic tumor microenvironment-related genes.