. 2020 Mar 24;25(6):1459. doi: 10.3390/molecules25061459

Table 4.

Reactivity of aryl and heteroaryl cyclic triolborates with N-Boc-4-iodophenylalanine.

graphic file with name molecules-25-01459-i008.jpg

Entry	Cyclic borate	R	Metal	pH	Product	Yield(%) ^a
1	2a	Ph	K	8.0	3a	98
2	2a	Ph	K	7.0	3a	67
3	2a	Ph	K	6.0	3a	56
4	2b	Ph	Li	8.0	3a	30
5	2c	Ph	Na	8.0	3a	90
6	2d	Ph	Cs	8.0	3a	47
7	2e	Ph	TBA	8.0	3a	22
8	2f	p-MeOPh	K	8.0	3af	98
9	2g	o-Tol	K	8.0	3ag	79^b
10	2h	m-NO₂Ph	K	8.0	3ah	72^b
11	2i	2-furanyl	K	8.0	3ai	87
12	2j	3-thiophenyl	K	8.0	3aj	63

^a The reaction was conducted at 60 °C.