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. 2020 Mar 26;7(3):e12388. doi: 10.2196/12388

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©Najmeh Khalili-Mahani, Atousa Assadi, Kate Li, Mahsa Mirgholami, Marie-Eve Rivard, Habib Benali, Kim Sawchuk, Bob De Schutter. Originally published in JMIR Mental Health (http://mental.jmir.org), 26.03.2020.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Mental Health, is properly cited. The complete bibliographic information, a link to the original publication on http://mental.jmir.org/, as well as this copyright and license information must be included.

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The profile of physiological signals changes over time. The only immediate significant game-related change was observed in heart rate and heart rate variability variables. HR: heart rate; HRV: heart rate variability.