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. 2020 Feb 28;12(3):636. doi: 10.3390/nu12030636

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Partial representation of the renin–angiotensin system that shows the metabolic steps in which angiotensinase activities are involved (A); means values ± standard errors of aspartyl aminopeptidase activity (AspAP) in liver-soluble (B) and membrane-bound (C) fractions; glutamyl aminopeptidase activity (GluAP) in liver-soluble (D) and membrane-bound (E) fractions; alanyl aminopeptidase activity (AlaAP) in liver-soluble (F) and membrane-bound (G) fractions; and cystinyl aminopeptidase activity (CysAP) in liver-soluble (H) and membrane-bound (I) fractions expressed as pmol/min/mg prot. S: standard diet, VOO: virgin olive oil diet, Bch: butter plus cholesterol diet. * indicates significant differences between VOO or Bch vs. S, * p < 0.05. # indicates significant differences between VOO and Bch, # p < 0.05. ACE: angiotensin converting enzyme; IRAP: insulin regulated aminopeptidase.