Table 6.
Phase 2: Hemodynamic properties and arterial stiffness.
| SHR | ||||
|---|---|---|---|---|
| Baseline | Black Beans for 8 Weeks |
Washout for 2 Weeks |
Washout for 4 Weeks |
|
| Hemodynamics | ||||
| DBP (mmHg) 1 | 123 ± 4 | 136 ± 6 | 141 ± 8 | 135 ± 12 |
| SBP (mmHg) 1 | 165 ± 5 | 187 ± 6 | 188 ± 10 | 187 ± 11 |
| MAP (mmHg) 1 | 137 ± 4 | 153 ± 6 | 156 ± 9 | 152 ± 12 |
| HR (bpm) 2 | 377 ± 9 b | 466 ± 14 a | 427 ± 14 a | 455 ± 34 a |
| HRV (bpm) 2 | 161 ± 3 a | 139 ± 3 b | 150 ± 3 b | 143 ± 7 b |
| Femoral artery stiffness | ||||
| PFV (cm/sec) | 31.8 ± 0.6 a | 28.9 ± 1.6 a,b | 25.2 ± 0.9 b | 27.3 ± 1.7 b |
| MinFV (cm/sec) | 3.5 ± 0.4 a | 0.2 ± 0.7 b | 1.6 ± 0.5 b | 1.5 ± 0.7 b |
| MFV (cm/sec) | 9.7 ± 0.5 a | 5.9 ± 0.5 b | 7.5 ± 0.6 b | 7.4 ± 1.2 b |
| Pulsatility index | 3.0 ± 0.1 b | 6.0 ± 1.3 a | 3.4 ± 0.3 b | 3.8 ± 0.4 b |
| Resistivity index | 0.89 ± 0.01 b | 0.99 ± 0.02 a | 0.94 ± 0.02 a,b | 0.95 ± 0.02 a,b |
Measurements obtained from 1 tail artery, 2 femoral artery. Data are expressed as mean ± SEM (n = 10/group at baseline and 8 weeks; n = 5/group for washout for 2 or 4 weeks). For means within the same row, different letters superscripts [a,b] represent significant differences (p < 0.05). An absence of letters indicates no statistical differences. Abbreviations: DBP, diastolic blood pressure; HR, heart rate; HRV, heart rate variability; MAP, mean arterial pressure; MinFV, minimum flow velocity; MFV, mean flow velocity; PFV, peak flow velocity; SHR, spontaneously hypertensive rats.