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. 2020 Feb 29;12(3):670. doi: 10.3390/nu12030670

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Dehydration alters hippocampal brain-derived neurotrophic factor (Bdnf) expression levels in young mice. (a) Brain weight was measured after the dehydration experiment in the control (CON) and dehydration group (DEH). (b) The expression of neurotrophic factors in the hippocampus and (c) of Bdnf mRNA in other brain regions (excluding the hippocampus) were assessed via qPCR. (d) The relationship between hippocampal Bdnf transcript and plasma osmolality levels was evaluated via a Pearson’s correlation analysis. Data are presented as the mean ± SEM. * p < 0.05 versus CON group according to a Student’s t-test. R² and p-values were calculated via a Pearson’s correlation analysis. NS, not statistically significant.