Table 2. Change in Nasal Congestion Bivariate Analysisa.
| Measure | Rhinitis | ||
|---|---|---|---|
| Allergic (n = 23) | Nonallergic (n = 67) | No rhinitis (n = 12) | |
| NOSE score | |||
| Baseline, mean (SD) | 44 (23) | 37 (26) | 32 (33) |
| 3-mo follow-up, mean (SD) | 35 (22) | 27 (23) | 17 (20) |
| Change (95% CI)b | −9 (−20 to 2) | −10 (−12 to −8) | −15 (−31 to 1) |
| Cohen d (95% CI)b | −0.4 (−0.9 to 0.1) | −0.4 (−0.5 to −0.3) | −0.5 (−0.9 to 0) |
| Clinically meaningful change, No. (%)c | |||
| Improved | 5 (22) | 21 (31) | 4 (33) |
| No change | 15 (65) | 42 (62) | 7 (58) |
| Worse | 4 (6) | 4 (6) | 1 (8) |
| Nasal congestion VAS score | |||
| Baseline, mean (SD) | 47 (29) | 39 (26) | 45 (31) |
| 3-mo, mean (SD) | 35 (28) | 33 (28) | 19 (21) |
| Change (95% CI)b | −12 (−20 to 0) | −6 (−13 to 1) | −26 (−36 to −16) |
| Cohen d (95% CI)b | −0.4 (−0.7 to 0) | −0.2 (−0.5 to 0) | −0.8 (−1.2 to −0.5) |
Abbreviations: NOSE, Nasal Obstruction Symptom Evaluation score; VAS, visual analog scale score.
a
NOSE and VAS scores range from 0 to 100, where 100 indicates worst congestion.
b
Change in nasal congestion at 3 months (negative is improvement).
c
Clinically meaningful change based on the anchor method (NOSE change 19).