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. 2020 Mar 10;12(3):726. doi: 10.3390/nu12030726

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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AC reduces hepatic lipogenesis and increases gluconeogenesis by regulating related-genes or protein in ob+/+ and ob/ob mice. (A) The relative mRNA expression of CD36, PPARγ, ME1, and SCD1 were compared between ob+/+Ctrl or ob/ob-Ctrl mice. (B,D) Immunoblot analysis of proteins involved in lipogenesis, β-oxidation, and gluconeogenesis. (C,E) Quantification of protein expression and comparison between ob+/+-Ctrl and ob/ob-Ctrl mice. All data are expressed as mean ± SEM, * p < 0.05, ** p < 0.01, *** p < 0.001. Non-significant; ns. n = 4–8 mice in each group. All experiments were repeated thrice.