Table 1.
Overview of the current literature on micronutrient deficiencies following esophagectomy.
| Author | Country | Year | Study Period | Study Design | Study population | Type of Surgery | Follow-up Period | Micronutrient Assessment | Prevalence of Deficiencies after Surgery | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Size | Age | Gender | |||||||||||||
| n | Years | (SD) or IQR | Male | % | Esophagectomy | Gastrectomy | Months | [IQR] | |||||||
| van Hagen et al. | Netherlands | 2017 | August 2010–July 2012 | Group A: single center, cross-sectional cohort study | 99 | 62 | 38–79 | 73 | 74 | 99 | – | 19.4 | [13.5–30.1] | Vitamin B12 | 11% |
| Group B: double center, prospective cohort study | 88 | 63 | 19–79 | 63 | 72 | 88 | – | 6.4 | [1.6–10.8] | Vitamin B12 | 10.2% | ||||
| Heneghan et al. | Ireland | 2015 | January 2013–July 2013 | Single center, prospective cohort study | 45 | 63.3 | (8.9) | 30 | 68 | 30 | 15 | 23.1 | [18,19,20,21,22,23,24,25,26,27,28] | Vitamin A Vitamin B12 Vitamin D Vitamin E Iron |
81.5% missing 44.4% 61.5% 46–49% |
| Elliot et al. | Ireland | 2019 | 2000–2014 | Single center, retrospective cohort study | 75 | 60.6 | (9.6) | 58 | 77 | 75 | – | 43.4 | Missing | Vitamin A Vitamin D Vitamin E |
missing 53%–70% † missing |
Legend: values mean (standard deviation) or median [lower-upper quartile]. † Serum vitamin D value <50 nmol/L.