Table 3.
A bivariable and multivariable logistic regression analysis result testing for factors associated with perinatal outcome (death/alive) among neonates delivered from preeclamptic women from 2011 to 2016 (before the effect of labor and early neonatal complication controlled)
| Variable | COR, (95% CI) | p-value | AOR, (95% CI) | p value | |
|---|---|---|---|---|---|
| Diastolic Blood pressure measurement (n = 231) | Less than 110 mmHg | 1 | 0.009 | 1 | 0.335 |
| ≥ 110 mmHg | 3.688(1.257–4.863) | 1.606(0.034–3.177) | |||
| Manifestation of end-organ involvement | Yes | 4.667 (1.332–8.001) | 0.012 | 4.404 (1.219–6.370) | 0.035* |
| No | 1 | 1 | |||
| Gestational age at birth | < 37 completed weeks | 2.547 (1.073–4.021) | 0.030 | 1.105 (0.098–2.111) | 0.315 |
| ≥ 37 completed weeks | 1 | 1 | |||
| Time lapsed from admission to initiation of MgSO4b (n = 139) | Less than 1 h | 1 | 1 | ||
| More than 1 h | 1.254 (0.343–2.164) | 0.751 | 2.780 (0.558–5.002) | 0.427 | |
| Time lapsed from admission to initiation of antihypertensivesc (n = 101) | Less than 17 min | 2.962 (0.331–5.593) | 0.669 | 3.636 (0.231–7.014) | 0.125 |
| 17–30 min | 3.436 (0.479–6.392) | 0.397 | |||
| 30 min to 1 h | 2.331 (0.195–4.467) | 0.931 | |||
| More than or equal to 1 h | 1 | 1 | |||
| Time lapsed from admission to onset of labord (n = 141) | Less than 35 h | 1 | 1 | 0.412 | |
| More than or equal to 35 h | 1.353 (0.235–2.452) | 0.644 | 1.951 (0.896–3.006) | ||
| Qualitative proteinuria (n = 223) | Mild proteinuria | 1 | 0.776 | 1 | 0.623 |
| Marked proteinuria | 1.395 (0.547–2.243) | 1.159 (0.113–2.091) | |||
| MgSO4 continues 24 h after delivery (n = 210) | Yes | 1 | 0.024 | 1 | |
| No | 3.132 (1.048–4.168) | 4.069 (0.896–6.347) | 0.221 | ||
| Intrapartum Fetal heart rate (n = 225) | Normal | 1 | 0.014 | 1 | 0.112 |
| Some abnormal records | 6.328 (2.069–10.587) | 4.846 (0.667–9.025) | |||
| Onset of labor | Spontaneous | 1 | 1 | 0.119 | |
| Induced | 5.580 (2.237–8.923) | 7.477 (0.633–14.322) | |||
| Labor and early neonatal complications (n = 239) | Yes | 3.454 (1.321–5.588) | 0.006 | 4.616 (1.365–7.867) | 0.017* |
| No | 1 | 1 | |||
| Fifth minute APGAR scorea (n = 214) | 0–3 | 13.962 (6.499–21.426) | 0.011 | 5.046 (1.856–8.235) | 0.0005* |
| 4–6 | 7.645 (2.629–12.660) | 0.003 | 3.112 (1.223–5.001) | 0.021* | |
| 7–10 | 1 | 1 | |||
Key: COR: Cruds odd ratio
*show association with p value less than 0.05
aanalysis was done after excluding stillbirths
bFor patients with severe preeclampsia and preeclampsia superimposed on chronic hypertension
cFor patients with DBP > 110 mmHg
dFor women with severe preeclampsia and preeclampsia superimposed on chronic hypertension