Fig. 2.

Probes-genes regulated by vitamin D2, vitamin D3 or differentiation alone at 24 and 72 h. (a) Values represent numbers of probes detecting differentially expressed genes compared with their respective control (adj. P. Val ≤ 0.05, testing significance relative to a 10%-fold change in expression using LIMMA TREAT (McCarthy & Smyth, 2009)). The Venn diagrams (b) show the number of probes specifically down-regulated (left) or up-regulated (right) by each vitamin or both. The control (Ctrl) 72 h vs Ctrl 24 h data is not represented in the Venn diagrams. (c) Hierarchical cluster analysis and heatmap of all the probes significantly different in any of the comparisons listed in panel a (5,565 probes). All the probes-genes are listed in Additional File 1, where information about the respective clusters is included