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. 2020 Apr 9;26:31. doi: 10.1186/s10020-020-00150-w

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© The Author(s) 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Upregulated miR-195 and downregulated KLF5 promoted synaptic plasticity. a Electron microscopy images in each group, the red arrow referring to the PSD (10,000 ×); b The number of synapses in each group presented by histogram; c The curvature of synaptic interfaces in each group presented by histogram; d The thickness of PSD in each group as illustrated by histogram; ^*, p < 0.05, compared with the control group; ^#, p < 0.05, compared with the WT-MCAO group; MCAO, middle cerebral artery occlusion; miR-195, microRNA-195; WT, wild type; KLF5, Kruppel-like factor 5; PSD, postsynaptic density