Table 2.
Memory function | P-value | ||||
---|---|---|---|---|---|
Best tertile N = 51 |
Middle tertile N = 54 |
Worst tertile N = 50 |
crude | adjusted | |
Age, mean (SE) | 73.8 (0.9) | 75.8 (0.9) | 78.7 (0.9) | < 0.001 | < 0.001* |
Gender, n (%) | 0.032 | 0.003* | |||
Female | 19 (37.3%) | 21 (38.9%) | 13 (26%) | ||
Male | 32 (63.7%) | 33 (61.1%) | 37 (74%) | ||
Higher educational level, n (%) | 17 (33.3%) | 20 (37.0%) | 10 (20.0%) | 0.003 | 0.001* |
eGFR, mean (SE) | 16.4 (0.7) | 16.1 (0.6) | 16.2 (0.6) | 0.922 | 0.664 |
ΔeGFR, mean (SE) | 10.1 (1.7) | 8.3 (1.0) | 9.1 (1.0) | 0.598 | 0.779 |
Urea, mean (SE) | 20.4 (0.8) | 20.9 (0.9) | 21.7 (0.8) | 0.904 | 0.582 |
Phosphate, mean (SE) | 1.3 (0.04) | 1.3 (0.03) | 1.3 (0.04) | 0.258 | 0.527 |
Calcium, mean (SE) | 2.3 (0.02) | 2.4 (0.02) | 2.3 (0.02) | 0.401 | 0.547 |
Vascular vs non-vascular cause, n (%) | 0.946 | 0.884 | |||
Vascular | 28 (56.0%) | 39 (72.2%) | 31 (63.2%) | ||
Non-vascular | 22 (44.0%) | 15 (27.7%) | 18 (36.7%) | ||
Ankle-Brachial index (right), mean (SE) | 0.98 (0.03) | 0.90 (0.04) | 0.99 (0.04) | 0.526 | 0.572 |
Presence of diabetes, n (%) | 18 (35.3%) | 24 (44.4%) | 21 (42.0%) | 0.195 | 0.286 |
History of vascular disease, n (%) | 19 (37.3%) | 26 (48.1%) | 28 (56%) | 0.004 | 0.163 |
Polypharmacy (≥5), n (%) | 43 (84.2%) | 51 (94.4) | 44 (88%) | 0.622 | 0.512 |
Fried Frailty Index, mean (SE) | 1.3 (0.2) | 1.6 (0.2) | 1.9 (0.2) | 0.055 | 0.082 |
IADL, mean (SE) | 2.0 (0.4) | 3.2 (0.5) | 4.6 (0.6) | < 0.001 | 0.003 |
Walking speed, mean (SE) | 1.2 (0.05) | 1.0 (0.04) | 1.2 (0.25) | 0.795 | 0.545 |
Handgrip strength, mean (SE) | 25.5 (1.4) | 24.4 (1.3) | 26.1 (1.4) | 0.527 | 0.529 |
Memory tested by the 15-WVLT. Tertiles of the 15-WVLT: best tertile mean 42.6 (SD 6.3) n = 51; middle tertile mean 29.7 (SD 2.8) n = 54; worst tertile mean 21 (SD 3.9) n = 50 Δ EGFR available for n = 41, n = 48, n = 39. Ankle-Brachial index available for n = 35, n = 37, n = 39. Walking speed available for n = 46, n = 50, n = 47. Model I: linear regression including correction for age, gender and educational level. *In model I age is only adjusted for gender and educational level; gender is only adjusted for age and educational level; educational level is only adjusted for age and gender