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. 2020 Apr 9;21:126. doi: 10.1186/s12882-020-01764-2

Table 2.

Associated characteristics of memory function

Memory function P-value
Best tertile
N = 51
Middle tertile
N = 54
Worst tertile
N = 50
crude adjusted
Age, mean (SE) 73.8 (0.9) 75.8 (0.9) 78.7 (0.9) < 0.001 < 0.001*
Gender, n (%) 0.032 0.003*
 Female 19 (37.3%) 21 (38.9%) 13 (26%)
 Male 32 (63.7%) 33 (61.1%) 37 (74%)
Higher educational level, n (%) 17 (33.3%) 20 (37.0%) 10 (20.0%) 0.003 0.001*
eGFR, mean (SE) 16.4 (0.7) 16.1 (0.6) 16.2 (0.6) 0.922 0.664
ΔeGFR, mean (SE) 10.1 (1.7) 8.3 (1.0) 9.1 (1.0) 0.598 0.779
Urea, mean (SE) 20.4 (0.8) 20.9 (0.9) 21.7 (0.8) 0.904 0.582
Phosphate, mean (SE) 1.3 (0.04) 1.3 (0.03) 1.3 (0.04) 0.258 0.527
Calcium, mean (SE) 2.3 (0.02) 2.4 (0.02) 2.3 (0.02) 0.401 0.547
Vascular vs non-vascular cause, n (%) 0.946 0.884
 Vascular 28 (56.0%) 39 (72.2%) 31 (63.2%)
 Non-vascular 22 (44.0%) 15 (27.7%) 18 (36.7%)
Ankle-Brachial index (right), mean (SE) 0.98 (0.03) 0.90 (0.04) 0.99 (0.04) 0.526 0.572
Presence of diabetes, n (%) 18 (35.3%) 24 (44.4%) 21 (42.0%) 0.195 0.286
History of vascular disease, n (%) 19 (37.3%) 26 (48.1%) 28 (56%) 0.004 0.163
Polypharmacy (≥5), n (%) 43 (84.2%) 51 (94.4) 44 (88%) 0.622 0.512
Fried Frailty Index, mean (SE) 1.3 (0.2) 1.6 (0.2) 1.9 (0.2) 0.055 0.082
IADL, mean (SE) 2.0 (0.4) 3.2 (0.5) 4.6 (0.6) < 0.001 0.003
Walking speed, mean (SE) 1.2 (0.05) 1.0 (0.04) 1.2 (0.25) 0.795 0.545
Handgrip strength, mean (SE) 25.5 (1.4) 24.4 (1.3) 26.1 (1.4) 0.527 0.529

Memory tested by the 15-WVLT. Tertiles of the 15-WVLT: best tertile mean 42.6 (SD 6.3) n = 51; middle tertile mean 29.7 (SD 2.8) n = 54; worst tertile mean 21 (SD 3.9) n = 50 Δ EGFR available for n = 41, n = 48, n = 39. Ankle-Brachial index available for n = 35, n = 37, n = 39. Walking speed available for n = 46, n = 50, n = 47. Model I: linear regression including correction for age, gender and educational level. *In model I age is only adjusted for gender and educational level; gender is only adjusted for age and educational level; educational level is only adjusted for age and gender