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. Author manuscript; available in PMC: 2020 Apr 10.
Published in final edited form as: Head Neck. 2019 Nov 24;42(4):774–786. doi: 10.1002/hed.26036

TABLE 3.

Oncologic characteristics

Primary tumor site, n (%)
Oropharyngeal
Author (year) N Pharyngeal All Eval HPV+ HPV− Nasal cavity Oral cavity Laryngeal Other
Cohen (2019) 247 a NA NA NA NA a a a a
Zandberg (2019) 112 40 (36) 40 37 20 17 0 47 (39) 15 (13) 1 (1)
Colevas (2018) 32 23 (72) 18 16 12 4 0 7 (22) 2 (6) 0
Ferris (2018)b 240 92 (38) NA NA NA NA 0 108 (45) 34 (14) 6 (3)
Mehra (2018)b 192 97 76 NA NA NA 12 28 18 37
Siu (2018) 67 33 (49) 25 NA NA NA 0 15 (22) 17 (25) 0
Bauml (2017) 171 108 (63) 100 NA NA NA 1 (1) 28 (16) 30 (18) 0
Hsu (2017) 27 27 (100) NA NA NA NA 0 0 0 0

Abbreviations: CPS, Combined Positive Score; if more than one methodology was reported, Combined Positive Score ≥ 1 was determined to indicated positivity; Eval, evaluable; IC, area of tumor area positive for immune cells; NA, not available; TC, tumor cell staining.

a

Not reported or not tested.

b

Data from most recent study are presented here; if data in most recent study were not specifically reported, then data from prior studies are reported.