. Author manuscript; available in PMC: 2020 Apr 10.

Published in final edited form as: Hematol Oncol Clin North Am. 2019 Feb;33(1):103–120. doi: 10.1016/j.hoc.2018.09.001

Table 3.

Histopathologic staging of lymph nodes

Classification	Dutch System	NCI Classification
N1	Grade 1 : Dermatopathic lymphadenopathy	LN0: No atypical lymphocytes LN1: Occasional, Isolated atypical lymphocytes LN2: many atypical lymphocytes In 3–6cellclusters
N2	Grade2: Dermatopathic lymphadenopathy, early involvement of MF	LN3: Aggregates of atypical lymphocytes; nodal architecture preserved
N3	Grade 3: Partial effacement of LN architecture; many atypical cells Grade 4: Complete effacement	LN4: Partial to complete effacement of nodal architecture by atypical lymphocytes

Republished with permission of American Society of Hematology, from Olsen E, Vonderheid E, Pimpinelli N, et al. Revisions to the staging and classification of mycosis fungoides and Sezary syndrome: a proposal of the International Society for Cutaneous Lymphomas (ISCL) and the cutaneous lymphoma task force of the European Organization of Research and Treatment of Cancer (EORTC). Blood 2007;110(6):1715; permission conveyed through Copyright Clearance Center, Inc.