Table 1.
Baseline characteristics of the study population (N = 78)
| General characteristics | |
| Sex (male), % | 66 |
| Age (years) | 62 ± 16 |
| Charlson index | 7.2 ± 2.7 |
| Diabetes, % | 30 |
| Hypertension, % | 90 |
| Dyslipidaemia, % | 60 |
| CKD aetiology, % | |
| Glomerular | 40 |
| Diabetes | 24 |
| Vascular | 17 |
| Interstitial | 9 |
| Polycystic kidney disease | 5 |
| Others | 5 |
| Dialysis features | |
| Dialysis vintage (months) | 27 (9–52) |
| Kt/Vurea | 2.0 ± 0.4 |
| Serum B2M (mg/dL) | 25.1 ± 7.5 |
| B2M reduction ratio, % | 79.2 ± 14.1 |
| OL-HDF, % | 82 ± 23 |
| Convective volume (L) | 28.7 ± 6.5 |
| Convective volume adjusted to ECW | 1.7 ± 0.5 |
| AV fistula, % | 66 ± 12 |
| Laboratory parameters | |
| YKL-40 (ng/mL) | 207 ± 106 |
| Haemoglobin (g/L) | 11.4 ± 1.1 |
| TSI (%) | 29.4 ± 10.1 |
| Albumin (g/dL) | 3.7 ± 0.3 |
| Prealbumin (mg/dL) | 23.5 ± 6.2 |
| CRP (mg/dL) | 0.4 (0.1–1.1) |
| Total cholesterol (mg/dL) | 142.5 ± 37.5 |
| Triglycerides (mg/dL) | 120.0 ± 64.2 |
| HbA1c (%) | 5.7 ± 1.0 |
| BNP (pg/mL) | 188 (90–408) |
| NT-proBNP (ng/dL) | 3450 (1350–8410) |
| Troponin T (ng/mL) | 53.1 (31.7–76.2) |
| Calcium (mg/dL) | 8.5 ± 0.6 |
| Phosphorus (mg/dL) | 4.1 ± 1.3 |
| PTH (pg/mL) | 420 (177–631) |
| Vitamin D (µg/L) | 10.3 ± 4.4 |
| Hydration status and body composition | |
| BMI (kg/m²) | 25.9 ± 4.9 |
| LTI (kg/m²) | 15.6 ± 4.0 |
| FTI (kg/m²) | 12.0 ± 9.3 |
| OH (L) | 1.3 (−0.02–2.2) |
| ECW (L) | 17.0 ± 3.5 |
| ICW (L) | 19.7 ± 4.7 |
| ECW/ICW | 0.8 ± 0.1 |
| OH/ECW (%) | 2.3 ± 0.8 |
| Medications | |
| Patients with antihypertensive treatment, % | 50 |
| Number of antihypertensive | 1.5 (0–3) |
| Patients with erythropoietin treatment, % | 89 |
| Doses erythropoietin per week (IU/week) | 4067 ± 1043 |
| Echocardiographic data | |
| LVEF (%) | 50 ± 10 |
| LVMI (g/m2) | 132 ± 45 |
Variables with this symbol were expressed as median IQR or mean ± SD.
OL HDF, Online hemodiafiltration; TSI, transferrin saturation index; BNP, brain natriuretic protein; BMI, body mass index; LTI, lean tissue index; FTI, fat tissue index; OH, overhydration; ECW, extracellular water; ICW, intracellular water; LVEF, left ventricular ejection fraction; LVMI, left ventricular mass index.