Table 3.
Patient characteristics by age and gender
| Patient characteristics | <60 years |
60–69 years |
70–79 years |
>79 years |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Women | Men | P-value | Women | Men | P-value | Women | Men | P-value | Women | Men | P-value | |
| Age, mean ± SD (years) | 49.6 ± 8.9 | 48.2 ± 9.7 | NS | 65.7 ± 2.9 | 65.7 ± 3.0 | NS | 75.5 ± 2.6 | 75.3 ± 2.5 | NS | 84.1 ± 3.7 | 84.4 ± 3.6 | NS |
| Vintage, mean ± SD (months) | 69.7 ± 68.4 | 65.5 ± 71.7 | NS | 61.9 ± 60.0 | 60.9 ± 66.6 | NS | 51.8 ± 44.8 | 55.8 ± 43.6 | NS | 61.1 ± 43.6 | 58.5 ± 56.2 | NS |
| BW, mean ± SD (kg) | 67.6 ± 17.2 | 73.8 ± 17.5 | 0.001 | 71.4 ± 16.7 | 74.1 ± 15.4 | NS | 68.6 ± 14.6 | 72.9 ± 13.5 | <0.01 | 63.1 ± 10.9 | 67.3 ± 11.7 | <0.01 |
| BMI, mean ± SD (kg/m2) | 25.3 ± 5.9 | 25.6 ± 5.6 | NS | 27.1 ± 5.9 | 26.3 ± 5.2 | NS | 26.5 ± 5.1 | 26.2 ± 4.7 | NS | 25.1 ± 4.5 | 24.7 ± 4.1 | NS |
| Kt/V, mean ± SD | 1.9 ± 0.42 | 1.7 ± 0.37 | <0.001 | 1.9 ± 0.39 | 1.7 ± 0.29 | <0.01 | 1.9 ± 0.44 | 1.8 ± 0.32 | NS | 2.0 ± 0.46 | 1.8 ± 0.29 | <0.001 |
| Kt/V > 1.2 (%) | 96 | 96 | NS | 98 | 98 | NS | 98 | 98 | NS | 98 | 97 | NS |
| Treatment time, mean ± SD (min) | 738 ± 63 | 737 ± 52 | NS | 737 ± 65 | 732 ± 70 | NS | 723 ± 49 | 728 ± 44 | NS | 719 ± 55 | 715 ± 47 | NS |
| Prescribed Qb, mean ± SD (mL/min) | 373 ± 48 | 384 ± 56 | 0.01 | 371 ± 46 | 384 ± 49 | NS | 370 ± 50 | 377 ± 46 | NS | 366 ± 39 | 370 ± 44 | NS |
| Treated blood volume, mean ± SD (L/kg) | 1.4 ± 0.4 | 1.3 ± 0.3 | NS | 1.3 ± 0.3 | 1.3 ± 0.3 | NS | 1.3 ± 0.4 | 1.3 ± 0.3 | NS | 1.4 ± 0.3 | 1.4 ± 0.3 | NS |
| Hb, mean ± SD (g/dL) | 10.9 ± 1.2 | 11.1 ± 1.4 | NS | 10.9 ± 1.1 | 11.2 ± 1.4 | NS | 11.0 ± 1.0 | 11.0 ± 1.4 | NS | 10.7 ± 1.2 | 10.9 ± 1.3 | NS |
| Hb 10–12 g/dL (%) | 65 | 64 | NS | 72 | 65 | NS | 76 | 64 | <0.05 | 69 | 69 | NS |
| TSAT, mean ± SD (%) | 31.6 ± 14.1 | 31.4 ± 15.3 | NS | 31.6 ± 14.6 | 31.2 ± 14.2 | NS | 30.1 ± 13.2 | 32.3 ± 16.0 | NS | 31.5 ± 14.5 | 30.6 ± 13.1 | NS |
| Ferritin, mean ± SD (µg/L) | 553 ± 439 | 514 ± 418 | NS | 653 ± 503 | 547 ± 401 | NS | 701 ± 683 | 598 ± 465 | NS | 698 ± 532 | 645 ± 487 | NS |
| Corrected weekly ESA, mean ± SD (U) | 4793 ± 5688 | 4229 ± 5740 | NS | 4224 ± 4714 | 4054 ± 4865 | NS | 4752 ± 5541 | 4029 ± 4943 | NS | 4244 ± 4283 | 4338 ± 5043 | NS |
| Albumin, mean ± SD (g/L) | 45.5 ± 4.3 | 44.4 ± 3.9 | NS | 41.3 ± 2.9 | 39.7 ± 4.2 | NS | 38.4 ± 3.9 | 39.5 ± 3.8 | <0.05 | 37.8 ± 5.0 | 38.3 ± 4.5 | NS |
| Calcium, mean ± SD (mg/dL) | 8.9 ± 0.8 | 8.8 ± 0.7 | NS | 8.8 ± 0.7 | 8.8 ± 0.7 | NS | 8.8 ± 0.7 | 8.8 ± 0.6 | NS | 8.9 ± 0.9 | 8.8 ± 0.7 | NS |
| Phosphorus, mean ± SD (mg/dL) | 4.8 ± 1.3 | 5.1 ± 1.5 | NS | 4.6 ± 1.3 | 4.4 ± 1.3 | NS | 4.3 ± 1.3 | 4.0 ± 1.2 | NS | 3.8 ± 1.2 | 3.8 ± 1.2 | NS |
| Phosphorus <5.5 mg/dL (%) | 70 | 68 | NS | 74 | 80 | NS | 85 | 93 | <0.05 | 93 | 93 | NS |
| iPTH, mean ± SD (pg/mL) | 648 ± 637 | 705 ± 531 | NS | 652 ± 708 | 548 ± 593 | NS | 501 ± 387 | 479 ± 392 | NS | 495 ± 480 | 464 ± 419 | NS |
| PTH 150–600 pg/mL (%) | 47 | 42 | NS | 50 | 62 | <0.05 | 54 | 57 | NS | 57 | 62 | NS |
| Pre-dialysis MAP, mean ± SD (mmHg) | 94 ± 15 | 97 ± 14 | NS | 93 ± 14 | 91 ± 13 | NS | 89 ± 12 | 88 ± 12 | NS | 83 ± 12 | 83 ± 12 | NS |
| IDBWG, percentage of BW, mean ± SD | 2.6 ± 1.4 | 2.7 ± 1.4 | NS | 2.3 ± 1.3 | 2.4 ± 1.4 | NS | 2.0 ± 1.2 | 2.1 ± 1.1 | NS | 2.0 ± 1.3 | 2.3 ± 3.3 | NS |
| Charlson comorbidity index, mean ± SD | 7.3 ± 3.1 | 6.6 ± 3.2 | 0.05 | 6.4 ± 2.8 | 7.0 ± 2.9 | NS | 6.9 ± 3.1 | 7.3 ± 2.9 | NS | 7.0 ± 2.9 | 7.3 ± 3.0 | NS |
| CVC (%) | 10 | 9 | NS | 19 | 11 | NS | 16 | 18 | NS | 28 | 24 | NS |
| AV fistula (%) | 78 | 83 | NS | 73 | 85 | <0.01 | 79 | 76 | NS | 61 | 73 | <0.05 |