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. 2020 Apr 3;11:383. doi: 10.3389/fphar.2020.00383

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Copyright © 2020 Song, Zhao, Wang, Wang, Chen, Zhao, Wang, Tian, Yu and Wu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of Zi Shen Huo Luo Formula (ZSHLF) on caveolin-1 (Cav-1) and mineralocorticoid receptor (MR) colocalization in aldosterone (ALD)-induced H9c2 cells and rat cardiac fibroblasts (RCFs). (A) Immunofluorescence labeling of Cav-1 (green) and MR (red) in H9c2 cells. (B) Immunofluorescence labeling of Cav-1 (green) and MR (red) in RCFs. (C) Effect of ZSHLF on Pearson’s r between Cav-1 and MR in H9c2 cells and RCFs. The data represent the mean ± standard deviation, n=3. ^#P < 0.05 vs. the BC group; ^◇P < 0.05 vs. the ALD group.