Table 1.

Components of Zi Shen Huo Luo Formula (ZSHLF) identified by UPLC-MS/MS analysis.

Peak No.	tR (min)	Measured [M-H]− (m/z)	Predicted [M-H]− (m/z)	△(ppm)	Formula	Identification	Derived from
1	0.23	278.1518	278.1517	0.3	C16H22O4	Dibutyl phthalate	A
2	0.28	162.0681	162.0680	0.36	C10H10O2	Methyl cinnamate	C
3	0.35	270.2559	270.2558	0.24	C17H34O2	Methyl palmitate	A
4	0.85	117.0790	117.0792	−1.62	C5H11O2	Betaine	A
5	0.89	143.0946	143.0945	0.96	C7H13NO2	DL-Stachydrine	D
6	6.59	152.1201	152.1202	−0.90	C10H16O	D-(+)-Camphor	C
7	6.64	180.0423	180.0418	2.39	C9H8O4	Caffeic acid	B
8	6.76	290.0790	290.0787	1.05	C15H14O6	Catechin	F
9	6.78	335.1158	335.1148	2.85	C20H17NO4	Berberine	E
10	7.60	152.0473	152.0474	−0.42	C8H8O3	Vanillin	E
11	8.47	168.0423	168.0441	−11.02	C8H8O4	Vanillic acid	B
12	8.52	302.0427	302.0425	0.65	C15H10O7	Quercetin	A
13	8.52	464.0955	464.0953	0.31	C21H20O12	Quercetin-β-D-glucoside	D
14	8.53	610.1534	610.1523	0.65	C27H30O16	Rutin	A
15	8.65	194.0580	194.0580	−0.65	C10H10O4	Ferulic acid	B
16	8.80	146.0368	146.0368	−0.04	C9H6O2	Coumarin	C
17	8.93	220.1827	220.1826	0.70	C15H24O	(−)-Caryophyllene oxide	C
18	9.28	286.0477	286.0477	0.12	C15H10O6	Kaempferol	A
19	10.41	188.1049	188.1035	7.5169	C9H16O4	Azelaic acid	A, C
20	11.11	594.1373	594.1362	1.89	C30H26O13	Tiliroside	D
21	13.18	270.0528	288.0629	1.42	C15H10O5	Apigenin	D
22	15.19	278.1518	278.1517	0.36	C16H22O4	Diisobutylphthalate	A
23	23.36	284.2715	284.2709	2.33	C18H36O2	Stearic acid	A

A, root of Achyranthes bidentata Bl.; B, root of Scrophularia ningpoensis Hemsl.; C, bark of Cinnamomum cassia Presl.; D, aerial part of Leonurus japonicus Houtt.; E, rhizome of Coptis chinensis Franch.; and F, root cortex of Paeonia suffruticosa Andr.