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(A) qRT-PCR Analysis of the gene expression levels of pro-inflammatory cytokines, chemokines, fibroblast-stimulating growth factors and macrophage fusion related genes in macrophages cocultured with PMMA or PMMA-MC materials at days 1, 4 and 7, *P < 0.05 denotes for significant difference as compared to the PMMA group. (B) Western blotting confirmation of the differentially expressed genes. (C) Schematic illustration shows the influence of MC particles on fibrous encapsulation of PMMA
