Table 1.
Participant Information
| ASD (n = 52) | TD (n = 50) | ||||
|---|---|---|---|---|---|
| Gender | 8 female | 8 female | |||
| Handedness | 7 left (0 female) | 7 left (0 female) | |||
| Mean (SD) | Range | Mean (SD) | Range | T, P-value | |
| Age in years | 13.7 (2.6) | 9.2–18.0 | 13.6 (2.6) | 8.0–17.6 | 0.29, P = 0.77 |
| Head motion | |||||
| RMSD precensoring | 0.065 (0.030) | 0.019–0.148 | 0.064 (0.032) | 0.017–0.148 | −0.20, P = 0.84 |
| RMSD after denoising | 0.003 (0.002) | 0.001–0.008 | 0.003 (0.003) | 0.001–0.014 | −0.94, P = 0.34 |
| Postcensoring TP | 178 (4.2) | 158–180 | 177 (3.9) | 166–180 | 0.25, P = 0.80 |
| WASI | |||||
| Verbal IQ | 102 (17.1) | 70–147 | 108 (9.1) | 87–126 | −2.14, P = 0.04 |
| Nonverbal IQ | 106 (17.2) | 53–140 | 105 (13.3) | 62–137 | 0.34, P = 0.73 |
| Full-scale IQ | 104 (16.4) | 66–141 | 107 (11.0) | 79–130 | −1.12, P = 0.26 |
| CELF-4a | |||||
| Core language | 99 (17.5) | 56–120 | 110 (9.1) | 91–126 | −3.18, P = 0.00 |
| Receptive | 99 (16.1) | 60–131 | 104 (11.2) | 76–127 | −1.22, P = 0.23 |
| Expressive | 97 (17.1) | 55–120 | 107 (8.9) | 91–124 | −2.96, P = 0.00 |
| ADOS-2b | |||||
| Social affect | 10.2 (3.7) | 5–20 | – | – | |
| Repetitive behavior | 3.4 (1.7) | 0–8 | – | – | |
| Total | 13.5 (4.2) | 5–24 | – | – | |
| Severity | 7.5 (1.9) | 3–10 | – | – | |
| ADI-R | – | – | |||
| Social interaction | 18.4 (4.9) | 7–28 | – | – | |
| Communication | 13.4 (5.1) | 2–24 | – | – | |
| Repetitive behavior | 6.1 (2.3) | 1–12 | – | – | |
Abbreviation: TP, time-points (180 total time-points before censoring).
a
CELF-4 scores were not available for 11 ASD and 12 TD participants.
b
38 ASD participants were assessed with Module 3 and 14 participants were assessed with Module 4 of the ADOS.