Table 2.
ROI | Brain Regions | Cluster Size | BA | MNI Coordinates (X, Y, Z) | t Value (df) | Effect Size |
---|---|---|---|---|---|---|
SZ0W vs HC | ||||||
Left dAI | Cluster 1 | 116 | ||||
Supplementary motor area | 6 | −8, −10, 64 | −3.46 (67) | −0.8118 | ||
Right dAI | Cluster 1 | 386 | ||||
Central precuneus | 7 | −16, −66, 44 | −3.56 (67) | −0.8353 | ||
Left PI | Cluster 1 | 438 | ||||
Left middle temporal gyrus | 22 | −56, −42, 6 | −2.90 (67) | −0.6804 | ||
Left superior temporal gyrus | 42 | −60, −44, 16 | −4.88 (67) | −1.145 | ||
Right PI | Cluster 1 | 186 | ||||
Right middle temporal gyrus | 21 | 66, −26, −10 | −4.01 (67) | −0.9409 | ||
Cluster2 | 97 | |||||
Right precuneus | 7 | 4, −60, 42 | −3.16 (67) | −0.7414 | ||
SZ8W vs SZ0W | ||||||
Left dAI | Cluster 1 | 163 | ||||
Supplementary motor area | 6 | 6, −14, 58 | 3.62 (33) | 1.2416 | ||
Right dAI | Cluster 1 | 163 | ||||
Posterior precuneus | 18 | 16, −76, 28 | −5.14 (33) | −1.763 | ||
Cluster 2 | 88 | |||||
Right middle temporal gyrus | 21 | 70, −32, −12 | 3.95 (33) | 1.3548 | ||
Left PI | Cluster 1 | 77 | ||||
Left middle temporal gyrus | 22 | −56, −36, 6 | 3.65 (33) | 1.2519 | ||
Left superior temporal gyrus | 42 | −62, −52, 22 | 4.34 (33) | 1.4886 | ||
Right PI | Cluster 1 | 88 | ||||
Right middle temporal gyrus | 21 | 68, −20, −2 | 4.63 (33) | 1.5881 | ||
Cluster 2 | 185 | |||||
Right precuneus | 7 | 6, −44, 34 | 3.87 (33) | 1.3274 | ||
Left vAI | Cluster 1 | 241 | ||||
Right inferior parietal lobule | 40 | 64, −36, 40 | −3.90 (33) | −1.3377 | ||
Right vAI | Cluster 1 | 118 | ||||
Right fusiform gyrus | 37 | 38, −46, −16 | 4.21 (33) | 1.444 |
Note: Bonferroni correction at P < .05, combined with AlphaSim correction at P < .008; MNI, Montreal Neurological Institute; BA, Brodman’s area; vAI, ventral anterior insula; dAI, dorsal anterior insula; PI, posterior insula. Effect size was measured by Cohen’s d.