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. 2020 Jan 4;46(3):623–632. doi: 10.1093/schbul/sbz112

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© The Author(s) 2020. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 1. — (A) Gap statistic to measure the number of optimum cluster in the data set using K-means clustering. The optimal solution for the morphological data from both patients and controls is the presence of three clusters. (B) The composition of each cluster, with 98%, 59%, and 67% of each cluster being comprised of patients, is shown. (C) Different patterns of cortical thinning in three clusters of patients (Cl, C2, and C3). The age- and gender-adjusted differences between patients in each cluster and the total sample of HCs are shown by the coloured cells (with red indicating Bonferroni-adjusted P < .05). The name of the corresponding regions from the Desikan–KIlliany atlas is shown in Supplementary Table 3.