Table 3.
Rates of Readmission and Mortality Within 365 Days in 4022 Patients with COPD Following Hospitalization Stratified by suPAR Quartiles or Blood Eosinophil Counts
| No Event | Respiratory Readmission | All-Cause Readmission | All-Cause Mortality | |
|---|---|---|---|---|
| 1275 (31.7%) | 1268 (31.5%) | 2326 (57.8%) | 1051 (26.1%) | |
| suPAR (ng/mL) | 3.3 (2.6–4.4) | 4.0 (2.9–5.5)* | 4.1 (3.0–5.7)* | 5.3 (3.8–7.1)* |
| First quartile (<2.9), n=980 | 437 (44.5%) | 309 (31.5%) | 511 (52.1%) | 109 (11.1%) |
| Second quartile (2.9–3.8), n=1003 | 388 (38.7%) | 286 (28.5%) | 551 (54.9%) | 175 (17.4%) |
| Third quartile (3.9–5.5), n=1014 | 268 (26.4%) | 365 (36.0%) | 643 (63.4%) | 287 (28.3%) |
| Fourth quartile (≥5.6), n=1025 | 182 (17.8%) | 308 (30.0%)* | 621 (60.6%)* | 480 (46.8%)* |
| Eosinophils (cells/μL) | 120 (30–250) | 100 (20–240)* | 100 (30–230)* | 50 (10–150)* |
| Low (<150), n=2366 | 678 (28.7%) | 735 (31.1%) | 1367 (57.8%) | 746 (31.5%) |
| Intermediate (150–300), n=886 | 312 (35.2%) | 266 (30.0%) | 520 (58.7%) | 169 (19.1%) |
| High (>300), n=597 | 222 (37.2%) | 218 (36.5%)* | 354 (59.3%)* | 86 (14.4%)* |
Notes: Values presented as percentages or median (IQR). Chi2-tests by increasing suPAR quartiles or blood eosinophil count groups, compared to patients without an event during the follow-up period. *p<0.05 in comparison to “No event”
Abbreviations: COPD, chronic obstructive pulmonary disease; IQR, interquartile range; suPAR, soluble urokinase plasminogen activator receptor.