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. Author manuscript; available in PMC: 2020 Apr 10.
Published in final edited form as: Clin Trials. 2019 Oct 24;17(1):77–86. doi: 10.1177/1740774519879932

Table 2:

Number of subjects (cases) with each of the selected type of events and the corresponding rate per 1000 patients years among subjects receiving the diuretic Chlorthalidone (C) versus the ACE inhibitor Lisinopril (L) versus the calcium channel blocker Amlodipine (A) in ALLHAT.

Amlodipine Lisinopril Chlorthalidone
n = 9,048 n = 9,054 n = 15,255
Outcome Cases Rate Cases Rate Cases Rate
Angina 950 23.6 1019 25.8 1567 23.2
Combined CVD 2432 65.4 2514 69.2 3941 62.8
Congestive Heart Failure 706 16.9 612 14.8 870 12.3
Combined Heart Failure 578 13.7 471 11.3 724 10.2
Stroke 377 8.9 457 10.9 675 9.5