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. 2009 Oct 17;21:35–68. doi: 10.1016/S0959-6380(09)70029-7

Table 1.

Antiviral Activity of Some Representative RENS

REN Structure Virus Antiviral Activity (μM) REN Structure Virus Antiviral Activity (μM)
graphic file with name fx1.gif HBV

  • *EC50= 0.13

  • SI > 18,500

 graphic file with name fx2.gif HSV

  • *EC50= 1.4

  • SI > 200
graphic file with name fx3.gif EBV

  • EC50= 8.8

  • SI > 193

 graphic file with name fx4.gif Rhino

  • EC50= 0.20

  • SI >500
graphic file with name fx5.gif RSV

  • EC50= 0.10

  • SI > 1000

 graphic file with name fx6.gif Measles

  • EC50= 0.50

  • SI > 200
graphic file with name fx4.gif vzv

  • EC50= 2.5

  • SI >100

 graphic file with name fx8.gif Influenza B

  • EC50= 65

  • SI > 150
graphic file with name fx9.gif HCV

  • EC50= 18

  • SI > 35

 graphic file with name fx10.gif WNV

  • EC50=0.51

  • SI > 195
*

EC50=effective concentration of the compound to reduce viral pathogenicity by 50%; SI=selectivity index=ratio of cytotoxic concentration of the compound to kill 50% of the normal cells to that required to kill 50% of the viral cells