Table 2.
Correlations Between Clinical Measurements and Bacterial Taxa or α-Diversity Measures
| Bacterial Measure | R | |
|---|---|---|
| PCOS Only (N = 37) | ||
| Free testosterone | Richness (Chao1) | −0.47** |
| Diversity (Shannon H) | −0.64** | |
| Evenness (Shannon H/Hmax) | −0.60** | |
| Total testosterone | Diversity (Shannon H) | −0.53** |
| Evenness (Shannon H/Hmax) | −0.52** | |
| Systolic blood pressure | (F) Streptococcaceae | 0.46 * |
| Waist:Hip ratio | (P) Firmicutes:Baceteriodetes ratio | 0.42* |
| (F) Bacteroidaceae | −0.43* | |
| ALT | (P) Firmicutes:Baceteriodetes ratio | 0.39* |
| (F) Bacteroidaceae | −0.39* | |
| Fasting triglyceride | (F) Ruminococcaceae | −0.46** |
| HOMA-IR‡ | (F) Lachnospiraceae | 0.41* |
| (F) Veillonellaceae | −0.51** | |
| All Participants (PCOS N = 37 + Control N = 21) | ||
| Free Testosterone § | Diversity (Shannon H) | −0.55** |
| Evenness (Shannon index) | −0.54** | |
| (F) Porphyromonadaceae | −0.396* | |
| Total testosterone | Diversity (Shannon H) | −0.55** |
| Evenness (Shannon H/H max) | −0.62* | |
| Systolic blood pressure | (F) Streptococcaceae | 0.38* |
| Waist:Hip ratio | (P) Bacteriodetes | −0.47* |
| (P) Firmicutes:Baceteriodetes ratio | 0.48** | |
| (F) Bacteroidaceae | −0.47* | |
| ALT | (P) Bacteriodetes | −0.43** |
| (P) Firmicutes:Baceteriodetes ratio | 0.44** | |
| (F) Bacteroidaceae | 0.47** | |
| (F) Porphyromonadaceae | −0.35* | |
| Fasting insulin‡ | (P) Bacteriodetes | −0.45** |
| (P) Firmicutes:Baceteriodetes ratio | 0.44* | |
| (F) Bacteroidaceae | −0.56** |
Correlations between clinical measures and bacterial taxa or measures of diversity with P values of <0.01 are shown. Abbreviations: ALT, alanine aminotransferase; F, family; P, phylum. *P < 0.01, **P < 0.001. §N = 7 for the control group. ‡N = 25 for the PCOS group.