Table 1.
Baseline Participant Characteristics
| n=90 | |
| Age (years)a | 49.9±16.4 |
| Male gender, n (%) | 57 (63.3) |
| Race, n (%) | |
| African-American | 3 (3.3) |
| American Indian | 2 (2.2) |
| Asian | 2 (2.2) |
| Pacific Islander | 3 (3.3) |
| White | 80 (88.9) |
| Ethnicity, n (%) | |
| Hispanic | 3 (3.3) |
| Non-Hispanic | 84 (93.3) |
| Unknown | 3 (3.3) |
| ALI risk factor, n (%) (not mutually exclusive) | |
| Trauma | 36 (40.0) |
| Shock | 36 (40.0) |
| Aspiration | 17 (18.9) |
| Sepsis | 14 (15.6) |
| Pneumonia | 12 (13.3) |
| Massive transfusion | 2 (2.2) |
| Moderate transfusion | 8 (8.9) |
| Overdose | 3 (3.3) |
| Near drowning | 1 (1.1) |
| Inhalation injury | 1 (1.1) |
| Admission Diagnosis, n (%) | |
| Trauma | 34 (37.8) |
| Sepsis | 13 (14.4) |
| Pneumonia | 9 (10.0) |
| Respiratory failure | 9 (10.0) |
| ALI/ARDS | 5 (5.6) |
| Intracranial hemorrhage | 5 (5.6) |
| Other | 15 (16.7) |
| APACHE II Scorea | 21.8±16.4 |
| PaO2/FiO2a | 164.4±58.2 |
| Tidal volume (mL/kg predicted body weight)a | 7.2±1.7 |
| Plateau pressure (cm H20)a | 24.6±5.5 |
| PEEP (cm H20)a | 9.1±4.0 |
| Lung Injury Score(Murray et al., 1988) a | 2.6±0.6 |
a
Data presented as mean ± standard deviation
Abbreviations: ALI = acute lung injury; ARDS = acute respiratory distress syndrome; APACHE = Acute Physiologic and Chronic Health Evaluation; PaO2/FiO2 = ratio of the partial pressure of arterial oxygen to the fraction of inspired oxygen; PEEP = positive end expiratory pressure.