Table 1.
HCT-CI [79].
| Comorbidity | Definition in HCT-CI | HCT-CI score |
|---|---|---|
| Arrhythmia | Atrial fibrillation or flutter, sick sinus syndrome, or ventricular arrhythmias | 1 |
| Cardiac | Coronary artery disease, congestive heart failure, myocardial infarction, or EF ≤ 50% | 1 |
| Gastrointestinal | Crohn’s disease or ulcerative colitis | 1 |
| Diabetes | Requiring insulin or oral hypoglycemic | 1 |
| Cerebrovascular disease | Transient ischemic attack (TIA) or cerebrovascular accident (CVA) | 1 |
| Psychiatric | Depression or anxiety requiring psychiatric consult or treatment | 1 |
| Hepatic, mild | Chronic hepatitis, bilirubin > ULN to 1.5× ULN, or AST/ALT> ULN to 2.5× ULN | 1 |
| Obesity | Patients with a body mass index (BMI) > 35 kg/m2 | 1 |
| Infection | Requiring continuation of antimicrobial treatment after day 0 | 1 |
| Rheumatologic | SLE, RA, polymyositis, mixed CTD, or PMR | 2 |
| Peptic ulcer | Requiring treatment | 2 |
| Moderate/severe renal | Serum creatinine >2 mg/dL, on dialysis, or prior renal transplantation | 2 |
| Moderate pulmonary | DLCO and/or FEV1 66–88% of dyspnea on slight activity | 2 |
| Prior solid tumor | Treated at any time point in the patient’s past history, excluding non-melanoma skin cancer | 3 |
| Heart valve disease | Except mitral valve disease | 3 |
| Severe pulmonary | DLCO and/or FEV1 ≤ 65% or dyspnea at rest or requiring oxygen | 3 |
| Moderate/severe hepatic | Liver cirrhosis, bilirubin >1.5× ULN, or AST/ALT >2.5× ULN | 3 |