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. Author manuscript; available in PMC: 2020 Apr 10.
Published in final edited form as: Eur Respir J. 2020 Mar 20;55(3):1901313. doi: 10.1183/13993003.01313-2019

Table 3.

Confirmation of pulmonary artery endothelial cell phenotype from representative samples

Subject No. Source CD-31 vWF VE-cadherin AcLDL uptake α-SMA
14 Control + + + + −
18 Idiopathic PAH, controlled hemodynamics + + + + −
13 HIV associated PAH, high PVR + + + + −
7 Portopulmonary hypertension, high CO, low PVR + + + + −

vWF=von Willebrand factor; VE=vascular endothelial; AcLDL=acetylated low density lipoprotein; α-SMA=alpha-smooth muscle cell actin; HPAECs=human pulmonary artery endothelial cells; ND=not done; PAH=pulmonary arterial hypertension; HIV=human immunodeficiency virus; PVR=pulmonary vascular resistance; CO=cardiac output. + indicates that 100% of the cells stained positive for antibody or took up AcLDL; − indicates that all cells were negative for antibody staining.