Table 4. Risk of various events in those with possible and probable HF, compared with definite HF.
Definite HF | Possible HF* | Probable HF† | p-value‡ | |
---|---|---|---|---|
A. CHD | ||||
Event Proportion, no. of events /no. at risk, (%) § | 77/479 (16) | 20/135 (15) | 16/121 (13) | |
Age-and-sex-adjusted Hazards Ratio (CI) | 1.00 REFERENT | 0.95 (0.58–1.56) | 0.69 (0.41–1.19) | 0.31 |
Multivariable-adjusted Hazards Ratio (CI) || | 1.00 REFERENT | 0.98 (0.57–1.67) | 0.63 (0.35–1.12) | 0.26 |
B. Other CVD | ||||
Event Proportion, no. of events /no. at risk, (%) § | 66/479 (14) | 18/135 (13) | 19/121 (16) | N/A |
Age-and-sex-adjusted Hazards Ratio (CI) | 1.00 REFERENT | 0.95 (0.56–1.60) | 0.96 (0.58–1.61) | 0.82 |
Multivariable-adjusted Hazards Ratio (CI) || | 1.00 REFERENT | 1.01 (0.58–1.76) | 1.03 (0.61–1.75) | 0.92 |
C. Death | ||||
Event Proportion, no. of events /no. at risk, (%) § | 429/479 (90) | 122/135 (90) | 106/121 (88) | N/A |
Age-and-sex-adjusted Hazards Ratio (CI) | 1.00 REFERENT | 1.13 (0.93–1.39) | 0.84 (0.68–1.04) | 0.74 |
Multivariable-adjusted Hazards Ratio (CI) || | 1.00 REFERENT | 1.21 (0.97–1.51) | 0.83 (0.66–1.05) | 0.97 |
* Meet HF criteria but have an alternative explanation for findings.
† Do not meet full criteria for definite HF.
‡ p-value for whether either pre-HF category as a whole predicts time to the outcome.
§ Event proportions are based on overall sample.
|| Model adjusted for age, sex, SBP, antihypertensive medications, current smoking, prevalent CHD, and body mass index.
HF = heart failure; CHD = coronary heart disease; CVD = cardiovascular disease.