KEY RESOURCES TABLE

REAGENT or RESOURCE	SOURCE	IDENTIFIER
Critical Commercial Assays
QIAGEN miRCURY RNA isolation kit	QIAGEN	76743
QIAGEN QIAamp DNA Micro Kit	QIAGEN	56304
Human 450K Infinium Methylation BeadChip	Illumina	WG-314–1003
SMARTer Stranded Total RNA-seq PICO v2 kit	Clontech/Takara	634414
Deposited Data
reference cell molecular profiles	GEO	see GSE138115 for sample Identifiers
Glioma tumor molecular profiles	TCGA	see GSE138115 for sample Identifiers
DNA methylation profiles of HBMVECs	This Paper	see GSE138115
RNA-seq profiles of HBMVECs	This Paper	see GSE138115
Experimental Models: Cell Lines
GBM8 primary GBM cells	Dr. Hiroaki Wakimoto	NA
Primary Human Brain Microvascular Endothelial Cells	Cell Systems	ACBRI-376
Oligonucleotides
Anti-miR-9: Cy5-TCATACAGCTAGATAACCAAAG	This Paper	NA
Software and Algorithms
exceRpt [v4.6.3] small RNA-seq pipeline	Rob Kitchen	https://github.com/rkitchen/exceRptgenboree.org
EDec	Onuchic et al., 2016	https://github.com/BRL-BCM/EDec
RnBeads	Assenov et al., 2014	rnbeads.org
GSEA	Broad Institute	http://software.broadinstitute.org/gsea/index.jsp
Other
EGM-2 MV Microvascular Endothelial SingleQuots Kit	Lonza	CC-4147
EBM-2 Endothelial Cell Growth Basal Medium-2	Lonza	CC-3156