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. 2020 Apr 10;6(15):eaax5150. doi: 10.1126/sciadv.aax5150

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Fig. 2 — (A) Analysis of differentially regulated transcripts at various levels. (B) Heatmap of identified, differentially regulated transcripts grouped by Spearman clustering. (C) Top enriched PANTHER reactome terms (gold) with parent categories (green). Doughnuts show distribution of transcript changes. (D) Mitochondrial DNA (mtDNA) quantification relative to nuclear DNA (nDNA) in Nkx2.5;1^KO2^KO and 1^FF2^FF E10.5 PHTs. (E) Atp5a, Slc25a24, and Got2 staining on Nkx2.5;1^KO2^KO and 1^FF2^FF E10.5 sagittal sections at AVC level with Hoechst nuclear counterstain. Grayscale images are unedited. tRNA, transfer RNA.