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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: AIDS. 2020 May 1;34(6):801–813. doi: 10.1097/QAD.0000000000002488

Figure 1: TIGIT is upregulated on NK cells from untreated HIV-infected women.

Figure 1:

(A) Schematic of study design and experiment. (B) A generalized linear model with bootstrap resampling was used to identify markers predictive of the study groups. Log-odds are logarithm of ratios of the probability that a cell belongs to each study subject. An increase in the parameter coefficient corresponds to the strength of the classification power, with the 95% confidence interval represented by line surrounding the point estimate. (C) Mean Signal Intensity of TIGIT on NK cells from healthy women (n=10), untreated HIV+ women (n=20), treated HIV+ women (n=17). * = unadjusted p-value≤0.05, ** = unadjusted p-value≤0.01, ns = non-significant.