Table 1.
Univariate and multivariate analysis of logistic regression of clinical characteristics correlated with high expression of both CD8 and CD4 dysfunctional populations.
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P | OR | 95% CI | P | |
| Age (<66 vs. ≥66 years) | 0.39 | 0.08–1.88 | 0.239 | |||
| Gender (Male vs. Female) | 1.72 | 0.68–4.34 | 0.252 | |||
| WHO/ISUP grade (1, 2 vs. 3, 4) | 3.48 | 1.39–8.73 | 0.008 | 3.48 | 1.39–8.73 | 0.008 |
| Clinical T stage (I, II vs. III, IV) | 1.66 | 0.69–4.03 | 0.261 | |||
| Coagulative necrosis (absence vs. presence) | 1.62 | 0.63–4.72 | 0.319 | |||
| Histological type (clear cell vs. non clear cell) | 0.50 | 0.10–2.51 | 0.399 | |||
| Lymphovascular invasion (No vs. Yes) | 2.37 | 0.97–5.82 | 0.059 | |||
| NLR (<3.45 vs. ≥3.45) | 3.17 | 1.31–7.68 | 0.011 | 0.106 | ||
| PLR (<1.61 vs. ≥1.61) | 3.33 | 1.35–8.21 | 0.009 | 0.121 | ||
| CRP (<1 mg/dL vs. ≥1 mg/dL) | 2.29 | 0.82–6.40 | 0.114 | |||
Abbreviations: OR = odds ratio, CI = confidence interval, NLR = neutrophil to lymphocyte ratio, PLR = platelet to lymphocyte ratio, CRP = C reactive protein.