Figure 1.

P. aeruginosa proteins with PAS and DGC/PDE domains. For each protein, the domain structure is shown on the right as determined by the SMART domain prediction server²⁵, with the sequence length also indicated. The observed sequence of the signature motifs for DGC domains (GGDEF) and PDE domains (EAL, DDFGTG) are given. Where enzymatic activity has been determined experimentally, this is indicated in green (or red, for no activity). Sequence alignment and homology modelling predicts the remaining proteins to be enzymatically active, as indicated by shading in green. NB. The N-terminal REC domain in FimX (residues 1-120) was not assigned by SMART²⁵ and is not shown here.